{"id":22814,"date":"2022-08-30T01:09:22","date_gmt":"2022-08-30T01:09:22","guid":{"rendered":"https:\/\/www.knowlative.com\/?p=22814"},"modified":"2022-08-30T01:09:22","modified_gmt":"2022-08-30T01:09:22","slug":"immune-system","status":"publish","type":"post","link":"https:\/\/www.knowlative.com\/it\/immune-system\/","title":{"rendered":"Immune System"},"content":{"rendered":"<div class=\"postie-post\"> <\/p>\n<p>The immune system is a host defence system comprising many biological structures and processes within an organism that protects against disease.<\/p>\n<p>To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism&#8217;s own healthy tissue.<\/p>\n<p>In many animals, there are two major subsystems of the immune system:<\/p>\n<ul>\n<li>the innate immune system and<\/li>\n<li>the adaptive immune system.<\/li>\n<\/ul>\n<p>Both subsystems use:<\/p>\n<ul>\n<li>humoral immunity and<\/li>\n<li>cell-mediated immunity to perform their functions.<\/li>\n<\/ul>\n<p>In humans, the blood\u2013brain barrier, blood\u2013cerebrospinal fluid barrier, and similar fluid\u2013brain barriers separate the peripheral immune system from the neuroimmune system, which protects the brain.<\/p>\n<p>Pathogens can rapidly evolve and adapt, and thereby avoid detection and neutralization by the immune system; however, multiple defence mechanisms have also evolved to recognize and neutralize pathogens. Even simple unicellular organisms such as bacteria possess a rudimentary immune system in the form of enzymes that protect against bacteriophage infections.<\/p>\n<p>Other basic immune mechanisms evolved in ancient eukaryotes and remain in their modern descendants, such as plants and invertebrates. These mechanisms include phagocytosis, antimicrobial peptides called defensins, and the complement system.<\/p>\n<p>Jawed vertebrates, including humans, have even more sophisticated defence mechanisms, including the ability to adapt over time to recognize specific pathogens more efficiently. Adaptive (or acquired) immunity creates immunological memory after an initial response to a specific pathogen, leading to an enhanced response to subsequent encounters with that same pathogen. This process of acquired immunity is the basis of vaccination.<\/p>\n<p>Disorders of the immune system can result in autoimmune diseases, inflammatory diseases and cancer. Immunodeficiency occurs when the immune system is less active than normal, resulting in recurring and life-threatening infections. In humans, immunodeficiency can either be the result of a genetic disease such as severe combined immunodeficiency, acquired conditions such as HIV\/AIDS, or the use of immunosuppressive medication. In contrast, autoimmunity results from a hyperactive immune system attacking normal tissues as if they were foreign organisms.<\/p>\n<p>Common autoimmune diseases include Hashimoto&#8217;s thyroiditis, rheumatoid arthritis, diabetes mellitus type 1, and systemic lupus erythematosus. Immunology covers the study of all aspects of the immune system.<\/p>\n<p> <\/p>\n<div class=\"postie-attachments\"><center><a href=\"https:\/\/www.knowlative.com\/wp-content\/uploads\/2022\/08\/Attachment-1-92-scaled.jpg\" class=\"et_pb_lightbox_image\" title=\"\"><span class=\"et_pb_image_wrap \"  style=\"max-height: 600px !important;\"><img loading=\"lazy\" src=\"https:\/\/www.knowlative.com\/wp-content\/uploads\/2022\/08\/Attachment-1-92-300x200.jpg\" alt=\"\" title=\"\" height=\"auto\" width=\"auto\" srcset=\"https:\/\/www.knowlative.com\/wp-content\/uploads\/2022\/08\/Attachment-1-92-scaled.jpg  500w, https:\/\/www.knowlative.com\/wp-content\/uploads\/2022\/08\/Attachment-1-92-300x200.jpg-480x480.jpg 480w\" sizes=\"(min-width: 0px; ) and (max-width: 480px) 480px, (min-width: 481px) 500px, 100vw\" class=\"wp-image-22815 \" style=\"max-height: 600px !important;\"><br \/>\n<\/span><\/a><\/center><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>The immune system is a host defence system comprising many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism&#8217;s own healthy tissue. In many animals, there [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":""},"categories":[81],"tags":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v18.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Immune System - Knowlative<\/title>\n<meta name=\"description\" content=\"Immune System\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.knowlative.com\/it\/immune-system\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Immune System - Knowlative\" \/>\n<meta property=\"og:description\" content=\"Immune System\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.knowlative.com\/it\/immune-system\/\" \/>\n<meta property=\"og:site_name\" content=\"Knowlative\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/Knowlative\" \/>\n<meta property=\"article:published_time\" content=\"2022-08-30T01:09:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.knowlative.com\/wp-content\/uploads\/2022\/08\/Attachment-1-92-300x200.jpg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Scritto da\" \/>\n\t<meta name=\"twitter:data1\" content=\"admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tempo di lettura stimato\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minuti\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.knowlative.com\/it\/#organization\",\"name\":\"Knowlative\",\"url\":\"https:\/\/www.knowlative.com\/it\/\",\"sameAs\":[\"https:\/\/www.facebook.com\/Knowlative\",\"https:\/\/www.instagram.com\/knowlative\/\",\"https:\/\/www.linkedin.com\/company\/knowlative\/about\/\"],\"logo\":{\"@type\":\"ImageObject\",\"@id\":\"https:\/\/www.knowlative.com\/it\/#logo\",\"inLanguage\":\"it-IT\",\"url\":\"https:\/\/www.knowlative.com\/wp-content\/uploads\/2021\/04\/knowlative.jpg\",\"contentUrl\":\"https:\/\/www.knowlative.com\/wp-content\/uploads\/2021\/04\/knowlative.jpg\",\"width\":2480,\"height\":603,\"caption\":\"Knowlative\"},\"image\":{\"@id\":\"https:\/\/www.knowlative.com\/it\/#logo\"}},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.knowlative.com\/it\/#website\",\"url\":\"https:\/\/www.knowlative.com\/it\/\",\"name\":\"Knowlative\",\"description\":\"The biggest online resource for muscle testers\",\"publisher\":{\"@id\":\"https:\/\/www.knowlative.com\/it\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.knowlative.com\/it\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"it-IT\"},{\"@type\":\"ImageObject\",\"@id\":\"https:\/\/www.knowlative.com\/it\/immune-system\/#primaryimage\",\"inLanguage\":\"it-IT\",\"url\":\"https:\/\/www.knowlative.com\/wp-content\/uploads\/2022\/08\/Attachment-1-92-300x200.jpg\",\"contentUrl\":\"https:\/\/www.knowlative.com\/wp-content\/uploads\/2022\/08\/Attachment-1-92-300x200.jpg\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.knowlative.com\/it\/immune-system\/#webpage\",\"url\":\"https:\/\/www.knowlative.com\/it\/immune-system\/\",\"name\":\"Immune System - 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